| Career Summary |
1991: Graduated/BEng (Faculty of Engineering, University of Tokyo)
1997: DEng (University of Tokyo)
1995-2001: Research Associate (Tohoku University)
2001-2002: Lecturer (Tohoku University)
2002-2005: Associate Professor (Tohoku University)
2005-present: Associate Professor (University of Tokyo)
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| Educational Activities |
Graduate school: Biological Chemistry, Physical Biochemistry
Undergraduate school: Molecular and Cellular Biology, Biochemistry
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| Research Activities |
Interaction Engineering (2005-present): regulation and design of protein interactions;
targets: antibodies, receptors, membrane proteins, scaffold proteins, and DNA.
Protein Manipulation (2005-present): refolding, liquid formulation.
Dissection of Diseases-related Proteins (2005-present)
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Literature
1) Ui, M., Tanaka, Y., Tsumuraya, T., Fujii, I., Inoue, M., Hirama, M., and Tsumoto, K.;
How Protein Recognizes Ladder-like Polycyclic Ethers: Interactions between
Ciguatoxin (CTX3C) Fragments and Its Specific Antibody 10C9. J. Biol. Chem., in
press (2008)
2) Hamada, D., Yanagihara, I., and Tsumoto, K.; Engineering Amyloidogenicity toward
Nanofibrillar Materials. Trends Biotechnol. 22, 93-97 (2004)
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| Other Activities |
Japanese Biochemical Society (JBS)
Protein Science Society of Japan (PSSJ)
Biophysical Society of Japan (BSJ)
Forum on Frontier Biological Chemistry (FBC)
Japanese Chemical Society (JCS)
American Chemical Society (ACS)
American Society for Biochemistry and Molecular Biology (ASBMB)
Protein Society of United States of America (PS)
American Association of Pharmaceutical Scientists (AAPS)
Associate Editor of Biochemistry
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| Future Plan |
We will investigate protein interactions from physical biochemical viewpoints,
including protein ligands, protein solvents, and protein-lipid interactions, for regulating
and designing biomolecular interactions. We plan to construct novel supramolecules
based on specific protein interactions.
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| Messages to Students |
I hope you will join us in our mission to regulate and design protein interactions. Our
method of applying interdisciplinary physical and chemical approaches to the biological
sciences would satisfy your interest in natural science and in society
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