Kiyoshi Kotani / Associate Professor /
Department of human and engineered environmental studies / / Biomedical Signal Rrocessing, Nonlinear Dynamics

Career Summary
1998: Graduated, Faculty of Engineering, The University of Tokyo
2003: Doctor of Engineering from The University of Tokyo
2003: Research Associate, The University of Tokyo
2006: Lecturer, The University of Tokyo
2011: Associate Professor, The University of Tokyo
Educational Activities
Graduate school:Theory of measurement and analysis of biomedical signals
Undergraduate school: Introduction to biology and physiology,
Mathematical principles for precision engineering
Research Activities
Analysis of heart rate variability (1998-)
The human heartbeat is governed by autonomic nervous activity. I proposed a method to analyze heart rate variability in the respiratory phase domain and illustrated its advantages for the evaluation of autonomic nervous activity. In addition, I proposed a model for cardio-vascular system which demonstrates
statistical physical properties of heart rate variability
such as multifractality.
1) K. Kotani, et al: Adjoint method provides phase response functions for delay-induced oscillations. Physical Review Letters 109, 044101, 2012.
2) I. Yamaguchi, et al: Reduction theories elucidate the origins of complex biological rhythms generated by interacting delay-induced oscillations. PLoS ONE 6: e26497, 2011.
3) K. Kotani, et al: Postural-induced phase shift of respiratory sinus arrhythmia and blood pressure variations - insight from respiratory-phase domain analysis. American Journal of Physiology, Heart and Circulatory Physiology, 294: H1481-H1489, 2008.
4) K. Kotani, et al: Investigation of the influence of swallowing, coughing, and vocalization on heart rate variability with respiratory-phase domain analysis. Methods of Information in Medicine, 46, pp.179-185, 2007.
5) K. Kotani, et al: Model for complex heart rate dynamics in health and diseases, Physical Review E, 72, pp.041904-1-8, 2005.

Other Activities

Future Plan
We aim to ellucidate the mechanisms of living systems with physical and physiological insights. Furthermore, we aim to apply them to support daily human activities.
Messages to Students
I hope that you will engage in your research with passion and curiosity.