Kazushige Touhara / Associate Professor / Division of Integrated Biosciences
Department of Integrated Biosciences / Molecular Recognition / Studies on odorant and pheromone reception in olfaction

Career Summary
1989: B.Sc. Department of Agricultural Chemistry, The University of Tokyo, Japan
1993 Ph.D. in Biological Chemistry from Department of Chemistry, State University of New York at Stony Brook, U.S.A.
1993-1995 Post-doctoral fellow, Duke University Medical Center
1995-1998 Assistant Professor, The University of Tokyo, School of Medicine, Department of Neurochemistry
1998-1999 Assistant Pprofessor, Kobe University, Biosignal Research Center
1999: Associate Professor, The University of Tokyo, Department of Integrated Biosciences
Educational Activities
Graduate School: Molecular recognition, Lessons in Writing Scientific Papers in English, Practice in Oral Presentation in English
Research Activities
Our research interests include elucidation of molecular mechanisms underlying odorant and pheromone perception in both vertebrates and invertebrates. To understand how the mouse olfactory system can discriminate thousands of odorants and how mice send socio-sexual information to other individuals by using specific pheromone molecules, we have focused on structural and functional aspects of odorant and pheromone receptors expressed by olfactory and vomeronasal sensory neurons, respectively. We also investigate signal transduction mechanisms in the insect olfactory system.
1) Oka, Y., Katada, S., Omura, M., Suwa, M., Yoshihara, Y. and Touhara, K. (2007) Neuron 52, 857-869
2) Fukuda, N., and Touhara, K. (2006) Genes to Cells 11, 71-81
3) Kimoto, H., Haga, S., Sato, K., and Touhara, K. (2005) Nature 437, 898-901
4) Nakagawa, T., Sakurai, T., Nishioka, T., and Touhara, K. (2005) Science 307, 1638-1642
5) Katada, S., Hirokawa, T., Oka, Y., Suwa, M., and Touhara, K. (2005) J. Neurosci. 25, 1806-1815
6) Sakurai, T., Nakagawa, T., Mitsuno, H., Mori, H., Endo, Y., Tanoue, S., Yasukochi, Y., Touhara, K., and Nishioka, T. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 16653-16658
7) Fukuda, N., Yomogida, K., Okabe, M., and Touhara, K. (2004) J. Cell Sci. 117, 5835-5845
8) Oka, Y., Omura, M., Kataoka, H., and Touhara, K. (2004) EMBO J. 23, 120-126
9) Kajiya, K., Inaki, K., Tanaka, M., Haga, T., Kataoka, H., and Touhara, K. (2001) J. Neuroscience 21, 6018-6025
10) Touhara, K., Sengoku, S., Inaki, K., Tsuboi, A., Hirono, J., Sato, T., Sakano, H., and Haga, T. (1999) Proc. Natl. Acad. Sci. USA 96, 4040-4045
Other Activities
Japanese Biochemical Society, Japanese Society of Molecular Biology, Japanese Society of Neurochemistry, Japanese Association for the Study of Taste and Smell, Japan Society for Bioscience, Biotechnology, and Agrochemistry, Association for Chemoreception Sciences (U.S.A.), Society for Neuroscience (U.S.A.), Member of American Association for the Advancement of Science (AAAS), Editorial board of Chemical Senses (2006-Present)
Future Plan
Messages to Students