Beate Heissig / Associate Professor / Division of Biosciences
Department of Computational Biology and Medical Sciences / / Stem Cell BiologyRegenerative MedicineCancer biology

Career Summary

1992: M.D. (Philipps-University Marburg, Germany)
1993: Doctor in Medicine (Philipps-University Marburg, Germany)
1991-1998: Clinical Fellow (The German National Bone Marrow Donor Program, Tuebingen; Oncology Department of Heidelberg University, and the Thoraxklinik, Germany), Hematology/Oncology, Germany.
1998-2002: Postdoctoral Fellow/Senior Research Associate (Memorial Sloan-Kettering Cancer Center and Weill Medical College of Cornell University, New York, USA)
2003-2004: Cooperative Assistant Professor (Juntendo University School of Medicine, Transfusion Medicine, Tokyo)
2004-2008: Project Assistant Professor (The Institute of Medical Science,University of Tokyo)
2008-2012: Project Associate Professor (The Institute of Medical Science,University of Tokyo, Frontier Research Initiative)
2014-present: Visiting Associate Professor (Juntento University School of Medicine, Tokyo)
2012-present: Associate Professor (Division of Stem Cell Dynamics, The Institute of Medical Science, University of Tokyo)

Educational Activities

Lectures for medical students at the Juntendo University School of Medicine on the topic of stem cell biology.

Research Activities

Since 2000, I have been investigating and characterizing the unique features of proteases as they relate to the regulation of stem cell behavior, blood vessel formation (angiogenesis), inflammation, and cancer. These studies will lead to the development of novel therapies in the growing field of regenerative medicine, cancer treatment, and immune diseases.


1) Sato, A. et al, Leukemia (2014)
2) Caiado, F. et al., Cancer Research (2013)
3) Tashiro, Y. et al., Blood (2012)
4) Nishida, C. et al., Blood (2012)
5) Okaji, Y. et al., Exp. Hematology (2012)
6) Ishihara, M. et al., Leukemia (2012)
7) Pia, J.H. et al., J Bio Chem (2011)
8) Ohki, M. et al., Blood (2010)
9) Kerbel R.S., et al., PNAS (2008)
10) Nishikii, H. et al., J Exp Med (2008)
11) Heissig B. et al., Cell Stem Cell (2007)
12) Jin, D.K. et al., Nat. Medicine (2006)
13) Heissig, B. et al., Nat. Medicine (2004)
14) Salven, P. et al., FASEB (2002)
15) Hattori, K. et al., Nat. Medicine (2002)
16) Heissig, B. et al., Cell (2002)

Other Activities

1) Member of the American Society of Hematology (2001-present)
2) Member of the American Association of Cancer Research (2003-present)
3) Member of the American Society for Cell Biology (2005-2009)
4) Member of the International Society for Stem Cell Research (2005-present)
1) American Society of Hematology Award (2002)
2) Ishibashi Memorial Lecture IMSJ (2004)
3) Associate Editor for Cancer Research (2007-2009)

Future Plan

The goal at our laboratory is to continuously advance our molecular and cellular understanding of stem cell-associated diseases and to identify novel therapeutic targets for diseases like cancer and inflammatory diseases.

Messages to Students

We welcome all of you who are interested in the fascinating scientific world of stem cells.